Corneal perception recovery drug containing amide compound

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S243000, C514S245000, C514S256000

Reexamination Certificate

active

07485654

ABSTRACT:
The amide compound of the formula (I) [each symbol is as defined in the description] has a promoting action on neuritogenesis of trigeminal nerve cells, and the compound is useful as a corneal neuritogenesis promoter, an agent for recovering corneal sensitivity by promotion of corneal neuritogenesis, and an agent for treating dry eye.

REFERENCES:
patent: 5958944 (1999-09-01), Arita et al.
patent: 6218410 (2001-04-01), Uehata et al.
patent: 6277855 (2001-08-01), Yerxa
patent: 6649625 (2003-11-01), Azuma et al.
patent: 6673812 (2004-01-01), Azuma et al.
patent: 7109208 (2006-09-01), Takayama et al.
patent: 2003/0125351 (2003-07-01), Azuma et al.
patent: 2004/0106646 (2004-06-01), Takayama et al.
patent: 2004/0162315 (2004-08-01), Hellberg et al.
patent: 2006/0234922 (2006-10-01), Takayama et al.
patent: 1 034 793 (2000-09-01), None
patent: 1 566 184 (2005-08-01), None
patent: 2004/039403 (2004-05-01), None
Saini Jagjit S, Mittal Sangeet, Graded corneal sensitivity for screening of diabetic retinopathy, Indian J Ophthalmology, 44(4), 219-223, 1996.
Saini Jagjit S, Mittal Sangeet, Graded Corneal Sensitivity for screening of diabetic retinopathy, Indian J. Ophthalmology, 44(4), 219-223, 1996.
T.U. Linna et al., “Recovery of Corneal Nerve Morphology Following Laserin situ Keratomileusis”, Exp. Eye Res., vol. 66, pp. 755-763, 1998.
T. U. Linna et al., “Effect of Myopic LASIK on Corneal Sensitivity and Morphology of Subbasal Nerves”, Investigative Ophthalmology & Visual Science, vol. 41, No. 2, pp. 393-397, Feb. 2000.
R. T. Ang et al., “Dry eye after refractive surgery”, Current Opinion in Ophthalmology, vol. 12, pp. 318-322, 2001.
P.H. Ozdinler et al., “Regulation of Neurotrophin-Induced Axonal Responses via Rho GTPases”, The Journal of Comparative Neurology, vol. 438, pp. 377-387, 2001.
M. Negishi et al., “Rho Family GTPases as Key Regulators for Neuronal Network Formation”, J. Biochem., vol. 132, No. 2, pp. 157-166, 2002.
J. Horwath-Winter et al., “Early changes in corneal sensation, ocular surface integrity, and tear-film function after laser-assisted subepithelial keratectomy”, J. Cataract Refract Surg., vol. 30, pp. 2316-2321, Nov. 2004.
K. Y. Chan et al., “Specificity of a Neuronotrophic Factor from Rabbit Corneal Epithelial Cultures”, Exp. Eye Res., vol. 41, pp. 687-699, 1985.
M. C. Argbelaez, “Nidek MK 2000 Microkeratome Clinical Evaltuation”, Journal of Refractive Surgery, vol. 18, pp. S357-S360, May/Jun. 2002.
Supplementary European Search Report dated Jul. 28, 2008 issued in connection with European Application No. 05 74 8492.5-1521 corresponding to the present U.S. application.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Corneal perception recovery drug containing amide compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Corneal perception recovery drug containing amide compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Corneal perception recovery drug containing amide compound will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4110771

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.