Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Eye prosthesis – Corneal implant
Patent
1993-10-13
1995-07-18
Jones, Mary Beth O.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Eye prosthesis
Corneal implant
351160H, 523105, 523114, A61F 216
Patent
active
054337453
ABSTRACT:
New corneal implants and methods for producing such implants are disclosed. The present corneal implants comprise a lens body which is optically clear and is structured to be surgically attached in or on the cornea of a mammalian eye, the lens body including a core having an outer surface and made of a hydrogel composition containing water and a hydrophilic polymeric material, and a coating comprising a synthetic polymeric component located on the outer surface, covalently bonded to the hydrogel composition and having enhanced ability to support epithelial cell growth and/or adhesion relative to the hydrogel composition.
REFERENCES:
patent: 3885078 (1975-05-01), Wichterle et al.
patent: 4388428 (1983-06-01), Kuzma et al.
patent: 4589964 (1986-05-01), Mayhan et al.
patent: 4693939 (1987-09-01), Ofstead
patent: 4806382 (1989-02-01), Goldberg et al.
patent: 4845132 (1989-07-01), Masuoka et al.
patent: 4851003 (1989-07-01), Lindstrom
patent: 4919659 (1990-04-01), Horbett et al.
patent: 4961954 (1990-10-01), Goldberg et al.
patent: 4983181 (1991-01-01), Civerchia
patent: 5007928 (1991-04-01), Okamura et al.
patent: 5108428 (1992-04-01), Capecchi et al.
patent: 5171318 (1992-12-01), Gibson et al.
patent: 5192316 (1993-03-01), Ting
Hino et al, A Study on Collagen-Plastic Composites as Biomaterials, "Biocompatibility of Tissue Analogs", vol. II, pp. 71-87.
Suzuki et al, Graft Copolymerization of Acrylamide onto a Polyethylene Surface Pretreated with a Glow Discharge, Macromolecules 1986, 1804-1808.
Yeh et al, Blood compatibility of surfaces modified by plasma polymerization, Journal of Biomedical Materials Research, vol. 22, 795-818 (1988).
Petit et al, Quanitation of Rabbit Corneal Epithelial Cell Outgrowth on Polymeric Substrates in Vitro, "Investigative Ophthalmology & Visual Science", vol. 31, No. 11, Nov. 1990.
Horbett et al, Hydrophilic-Hydrophobic Copolymers as Cell Substrates: Effect on 3T3 Cell Growth Rates, Journal of Colloid and Interface Science, vol. 104, No. 1, Mar. 1985.
Dreyfuss et al, Graft Copolymers, vol. 7, pp. 551-579 "Encyclopedia of Polymer Science and Engineering".
Gombotz et al, Gas-Discharge Techniques for Biomaterial Modification, vol. 4, Issue 1 (1987) pp. 1-42, "Critical Reviews in Biocompatibility".
Lydon et al, Cellular interactions with synthetic polymer surfaces in culture, Biomaterials 1985, vol. 6 Nov., pp. 396-402.
Kaplan et al, Medical Polymers and Plasma Technology, Technical Notes, Plasma Science, Foster City, California pp. 1-5.
On The Surface, vol. II, No. I, Improved Biocompatibility by Surface Modification, Metro-Line Industries, Inc. Corona, California.
Special Report, Using Gas Plasma to Reengineer Surfaces, Nancy B. Mateo, Reprinted from Medical Product Manufacturing News, Sep./Oct. 1990 pp. 1-2.
Dekker et al, Adhesion of endothelial cells and adsorption of serum proteins on gas plasma-treated polytetrafluoroethylene, Biomaterials 1991, vol. 12 Mar., pp. 130-138.
H. Boenig, Plasma Polymerization, vol. 11, pp. 249-261, Academic Press, Inc., Orlando, Fla. 1986 "Encyclopedia of Polymer Science and Engineering".
Ratner et al, Plasma Deposition and Treatment for Biomaterial Applications, "Plasma Deposition of Polymer Films", Academic Press, Boston 1989.
Cunanan Crystal M.
Francese James E.
Graham Richard S.
Allergan Inc.
Jones Mary Beth O.
Peterson Gordon L.
Uxa, Jr. Frank J.
LandOfFree
Corneal implants and methods for producing same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Corneal implants and methods for producing same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Corneal implants and methods for producing same will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2417668