Cornea storage medium

Details Cornea storage medium Cornea storage medium

1987-09-02

1989-10-10

Rosen, Sam

Chemistry: molecular biology and microbiology

Differentiated tissue or organ other than blood, per se, or...

Including perfusion; composition therefor

A01N 102

Patent

active

048731862

ABSTRACT:
A storage medium for isolated donor corneas comprising at least one compound capable of inhibiting corneal lactate production. The addition of a short chain fatty acid and/or a ketone body and precursors provides isolated corneas with an efficient fuel source and concurrently inhibits corneal lactate formation.

REFERENCES:
patent: 4663289 (1987-05-01), Veech
patent: 4695536 (1987-09-01), Lindstrom et al.
Messmer et al.-Chem. Abst., vol. 86 (1977), p. 151, 059c.
Sheu et al.-Chem. Abst., vol. 83 (1975), p. 173, 227w.
Bassenge et al., Am. J. Physiol., 208:162 (1965).
Krebs, H. A., (1972), The Pasteur Effect Essays Biochem., 8:2-34.
Williamson, Biochem. Soc. Transactions, 7:1313-1321 (1979).
Lindstrom et al., Dev. Ophthal., 11:37-43 (1985).
Lindstrom et al., American Journal of Ophthamology, vol. 82, No. 1, pp. 72-82 (Jul. 1976).
Lindstrom et al., Arch. Ophthalmol., 95:869-878 (May, 1977).
Veech et al., Biochem. J., 115:609-619 (1969).
Veech et al., J. of Biological Chem., vol. 254, No. 14, pp. 6538-6547 (Jul. 25, 1979).
Veech et al., Febs Letters, vol. 117, Supplement, Aug. 25, 1980, K65-72 (Elsevier/North-Holland Biomedical Press).
McCarey et al., Investigative Ophthamology, pp. 165-173 (Mar. 1974).

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