Coriolin derivatives

Details Coriolin derivatives Coriolin derivatives

1979-05-23

1980-11-11

Milestone, Norma S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D49320, C07D49322

Patent

active

042332249

ABSTRACT:
Anti-tumor low-toxicity coriolin derivatives represented by the following general formula: ##STR1## wherein one of X and Y is ##STR2## and the other is >C OH, >C.dbd.O or ##STR3##

REFERENCES:
Umezawa et al., "Coriolin, A New Basidiomycetes Zntibiotic", J. Antibiotics, XXII, 215-217 (1969).
Umezawa et al., "Diketocoriolin B, An Active Derivative of Coriolin B Produced by Coriolus Consors", J. Antibiotics, XXIV, 631-635 (1971).
Umezawa et al., "Revised Structure and Stereochemistry of Coriolins", Tetrahedron Letters, 22, 1955-1958 (1971).
Chemical Abstracts, vol. 79 (1973) 144864p.
E. Ohler et al., Angew. Chem. Internat. Edit., vol. 9 (1970) No. 6, 457-458.
H. O. House, Modern Synthetic Reactions, 2nd ed. (1972) pp. 264-265.
Houben-Weyl, Methoden der Organischen Chemie, vol. VII/2a, Part 1 (1973) pp. 734-737.

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