Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Reexamination Certificate
2005-04-19
2005-04-19
Le, H. Thi (Department: 1773)
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
C525S902000
Reexamination Certificate
active
06881484
ABSTRACT:
A core-shell particle including a signal-generating substance therein, wherein the core-shell particle consists of (1) a core portion substantially made of a water-insoluble polymer compound; and (2) a shell portion substantially made of a water-soluble polymer compound having a reactive functional group, and covering a surface of the core portion in the manner of bristles of a brush; and the core portion and the shell portion are, as a whole, a block copolymer of a water-insoluble polymer and a water-soluble polymer, characterized in that the signal-generating substance is included in the core portion, is disclosed, and a process for producing the same is also disclosed.The core-shell particle including a signal-generating substance therein is useful as a labeling substance in which neither radioisotopes having handling restrictions nor unstable enzymes are required, a high sensitivity superior to fluorescent substances is achieved, and nonspecific absorption does not occur.
REFERENCES:
patent: 5395688 (1995-03-01), Shah et al.
patent: 6444261 (2002-09-01), Plaksine et al.
patent: 0 305 212 (1989-03-01), None
patent: 0 822 217 (1998-02-01), None
patent: WO 0155722 (2001-08-01), None
patent: 5-262809 (1993-10-01), None
patent: 10-195152 (1998-07-01), None
patent: 2000-500798 (2000-01-01), None
patent: 2001-324507 (2000-11-01), None
patent: 2001-66312 (2001-03-01), None
patent: 2001-208754 (2001-08-01), None
patent: 2002-80903 (2002-03-01), None
Kalinina et al, “A Core-Shell Approach To Producing 3D Polymer Manocomposites” 1999, Macromolecules, American Chemical Society, pp. 4122-4129. (XP-000984727).
Hoshino Nobuhiro
Kataoka Kazunori
Nagasaki Yukio
Shibata Naoya
Le H. Thi
Mitsubishi Kagaku Iatron, Inc.
Nanocarrier Co., Ltd.
Sughrue & Mion, PLLC
LandOfFree
Core-shell particle including signal-generating substance... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Core-shell particle including signal-generating substance..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Core-shell particle including signal-generating substance... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3433534