Copper(II) nuclease compounds, compositions, and kits

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Enzyme inactivation by chemical treatment

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435 6, 435195, 435196, 435199, 436 2, 436 73, 436 80, 436 91, 436106, 436145, 514 1, 514183, 514499, 514740, 514742, 540 1, 549200, 549346, C12N 999, C07H 2100

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057390223

ABSTRACT:
A method is provided for nonoxidatively cleaving the phosphorus-oxygen linkage of nucleic acids and certain anticholinesterases such as insecticides using a macrocyclic copper(II) complex. A composition suited for such cleavage is also provided.

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