Copper-catalysed ligation of azides and acetylenes

Details Copper-catalysed ligation of azides and acetylenes Copper-catalysed ligation of azides and acetylenes

2003-05-30

2008-05-20

Powers, Fiona T (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07375234

ABSTRACT:
A metal catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to give triazoles. In many instances, the reaction sequence regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,3]-triazoles.

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