Copolymers of lactide and/or glycolide with 1,5-dioxepan-2-one

Surgery – Truss – Pad

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Details

528354, A61L 1700, C08G 6308

Patent

active

044704160

ABSTRACT:
Copolymers are prepared from 1,5-dioxepan-2-one and lactide and/or glycolide. The copolymers are useful in surgical applications such as sutures, suture lubricants, and allied surgical products. 1,5-Dioxepan-2-one is produced by a new process comprising first reacting ethylene glycol with an alkyl acrylate to form alkyl 3-(2-hydroxyethoxy)propionate, which is then cyclized by contacting with a trans-esterification catalyst.

REFERENCES:
patent: 4052988 (1977-10-01), Doddi et al.
patent: 4137921 (1979-02-01), Okuzumi et al.
patent: 4190720 (1980-02-01), Shalaby
patent: 4273920 (1981-06-01), Nevin

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