Copolymers having bactericidal activity, process for the prepara

Details Copolymers having bactericidal activity, process for the prepara Copolymers having bactericidal activity, process for the prepara

1982-01-04

1984-07-10

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424DIG2, 424DIG4, 424 49, 424 69, 424 78, 424361, 424362, A61K 3173, A61K 7035

Patent

active

044592892

ABSTRACT:
Copolymers of formula I are described ##STR1## in which A is the monomeric unit of a natural or synthetic polymer, m is the degree of polymerization; m and n are different one from the other, and m is a number between about 300 and about 10,000 and n is a number between about 100 and about 250; R is a quaternary ammonium radical; X.sup.- is an anion. A may be the monomeric unit of starch or the monomeric unit of hydroxyethylcellulose. The substances exhibit substantial activity in the treatment of infections of the skin and mucosa and fungus infections and in general, high bactericidal activity accompanied by low toxicity.

REFERENCES:
patent: Re26510 (1968-12-01), Mazzarella et al.
patent: 3567420 (1971-03-01), Legator et al.
patent: 4035146 (1977-07-01), Brenner et al.
patent: 4080346 (1978-03-01), Bedell
patent: 4131576 (1978-12-01), Iovine et al.
patent: 4144326 (1979-03-01), Luedicke, Jr.
patent: 4155885 (1979-05-01), Racciato et al.
patent: 4285973 (1981-08-01), Edwards
Research Disclosure No. 131 3/75, Union Carbide Corp., New York, N.Y., "Aqueous Cosmetic Cream Composition".

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