Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2006-08-01
2006-08-01
Chin, Christopher L. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C385S004000, C385S008000, C385S009000, C385S012000, C385S129000, C422S082010, C435S006120, C435S007100, C435S007920, C435S287100, C435S287200, C436S149000, C436S150000, C436S151000, C436S517000, C436S524000, C436S525000, C436S805000, C436S806000
Reexamination Certificate
active
07083985
ABSTRACT:
A coplanar waveguide biosensor and methods of use include a coplanar waveguide transmission line and a sample containment structure. The coplanar waveguide transmission line is operable to support the propagation of an electromagnetic signal and includes a signal line and one or more spaced apart ground elements. The signal line is configured to conduct a time-varying voltage, and the one or more ground elements are configured to maintain a time-invariant voltage, a detection region being formed between a portion of the signal line and a portion of at least one of the one or more ground elements. Detection methods are improved through the enhancement of the electric field in the detection region via impedance discontinuities in the signal line and ground elements. The sample containment structure intersects the detection region of the coplanar waveguide transmission line and includes a cavity configured to hold 1 ml or less of sample solution within the detection region.
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Hefti et al., “Sensitive Detection Method of Dielectric Dispersions in Aqueous-Based, Surface-Bound Macromolecular Structures Using Microwave Spectroscopy” Applied Physics Letters, American Institure of Physics. New York, US, vol. 75, No. 12, pp. 1802-1804 (1999).
Bartell Barrett
Hefti John J.
Kramer Kurt
Rhodes Mark A.
Chin Christopher L.
Howard Kelvan P.
Neeley Richard
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