Coordination complexes of platinum with amides

Details Coordination complexes of platinum with amides Coordination complexes of platinum with amides

1988-02-22

1989-08-08

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564218, 564219, 564318, 564391, 564488, C07C103127, C07C10334, C07C 8728, C07C 9308

Patent

active

048554987

ABSTRACT:
Disclosed are platinum (IV) chelates derived from substituted amides. The chelates result from the reaction under mild conditions of potassium chloroplatinate (II) and the appropriate amide. The chelate transdichloro-cis-bis(dimethylacetamide-C,O) was prepared, fully characterized and exemplified in preparation of the antihistamine diphenhydramine hydrochloride.

REFERENCES:
patent: 3266988 (1966-08-01), Saunders

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