Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Reexamination Certificate
2006-05-23
2010-06-22
Mosher, Mary E (Department: 1648)
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
C436S512000, C436S513000, C436S086000
Reexamination Certificate
active
07741128
ABSTRACT:
The present invention relates to methods and compositions to detect analytes in a sample using antibody molecules that are transformed into nanoscale “self-signaling” biosensors. It relates in particular to those methods and compositions that provide for single-step detection of target analytes without the need for labor-intensive steps necessary in conventional assays.
REFERENCES:
patent: 5981199 (1999-11-01), Ueda et al.
patent: 6162903 (2000-12-01), Trowern et al.
patent: 6822075 (2004-11-01), Björck et al.
patent: 6884629 (2005-04-01), Gore et al.
patent: 2003/0073149 (2003-04-01), Archer
patent: 2004/0110245 (2004-06-01), Nagamune et al.
patent: 2006/0068502 (2006-03-01), Su
patent: 1 382 965 (2004-01-01), None
patent: WO 2005033130 (2005-04-01), None
patent: WO 2005/089409 (2005-09-01), None
patent: WO 2005/042695 (2005-12-01), None
Akerstrom and Bjorck, Protein L: An Immunoglobulin Light Chain-binding Bacterial Protein: Characterization of Binding and Physicochemical Properties. J Biol Chem. vol. 264, No. 33, Issue of Nov. 25, pp. 19740-19746 1989.
Nielsen, et al. A homogeneous fluorescence polarization assay for detection of antibody toBrucella abortus. Journal of Immunological Methods 195 (1996) 161-168.
Szollo9si, et al. Cytometry (Communications in Clinical Cytometry) 34:159-179 (1998).
Kurstak, E. Progress in enzyme immunoassays: Production of reagents, experimental design, and interpretation. Bull. WHO. 1985; 63(4):793-811.
Åkerström and Björck. Protein L: An Immunoglobulin Light Chain-binding Bacterial Protein: Characterization of Binding and Physicochemical Properties. J. Biol. Chem. 1989; 264(33):19740-1976.
Aoki, et al. Construction of a fusion protein between protein A and green fluorescent protein and its application to Western blotting, FEBS Letters. 1996; 384:193-197.
Rogers, et al. Immunohistochemical Localization of Feline Immunodeficiency Virus Using Native Species Antibodies. Am. J. Pathol. 2002; 161(4): 1143-1151.
Green, NM Avidin and Streptavidin. Met. Enzymol. 1990; 184:51-67.
Arai, et al. Demonstration of a Homogeneous Noncompetitive Immunoassay Based on Bioluminescence Resonance Energy Transfer. Anal. Biochem. 2001; 289: 77-81.
Adams, S.R. et al. 2002. New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications.J Am Chem Soc. 124(21):6063-76.
Chin, J.W. et al. “Addition of a photocrosslinking amino acide to the genetic code ofEscherichia coli,” 2002(a).Proc Natl Acad Sci U S A99:11020-11024.
Chin, J.W. et al., “In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis,” 2002(b).Chembiochem3:1135-1137.
Clamme, J.-P. and Ashok A. Deniz. 2005. Three-Color Single-Molecule Fluorescence Resonance Energy Transfer.ChemPhysChem6: 74-77.
De Chateau, M. et al., <<On the Interaction between Protein L and Immunoglobulins of Various Mammalian Species, >> 1993.Scand J Immunol37:399-405.
Deo, S.K. 2004. Exploring bioanalytical applications of assisted protein reassembly.Anal Bioanal Chem379: 383-390.
Farrell, I.S. et al., “Photo-cross-linking interacting proteins with a genetically encoded benzophenone,” 2005.Nat Methods2:377-384.
Galarneau, A. et al., β-Lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein-protein interactions, >> 2002.Nat Biotechnol20:619-622.
Galperin, E. et al. 2004. Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells.Nature Methods1(3): 209-217.
Gao, W. et al. 2003. Novel Fluorogenic Substrates for Imaging beta-Lactamase Gene Expression.J. Am. Chem. Soc. 125(37):11146-11147.
Kastern, W. et al. 1992. Structure of peptostreptococcal protein L and identification of a repeated immunoglobulin light chain-binding domain.J. Biol. Chem. 267, 12820-5.
Komiya, N. et al., << Homogenous sandwich immunoassay based on the enxymatic complementation induced by single-chain Fv fragments, >> 2004.Anal Biochem327:241-246.
Li, F. et al., << Homogenous Noncompetitive Immunoassay Based on the Energy Transfer Between Fluoro-labeled Antibody Variable Domains (Open Sandwich Fluoroimmunoassay), 1999.Biotechniques27:738-742.
Lichlyter, D.J et al., << Development of a novel FRET immunosensor technique, >> 2003.Biosens Bioelectron19:219-226.
Lindhout, D.A. et al. 2004. NMR solution structure of a highly stable de novo heterodimeric coiled-coil.Biopolymers75(5):367-75.
Medintz, I.L. et al., << Self-assembled nanoscale biosensors based on quantum dot FRET donors, >> 2003.Nat Mater2:630-638.
Ohiro, Y. et al., << A Homogenous and Noncompetitive Immunoassay Based on the Enhanced Fluorescence Resonance Energy Transfer by Leucine Zipper Interaction, >> 2002.Anal Chem74:5786-5792.
Presta, L. 2003. Antibody engineering for therapeutics.Current Opinion in Structural Biology2003, 13:519-525.
Renard, M. et al., ,,Knowledge-based Design of Reagentless Fluorescent Biosensors from Recombinant Antibodies, 2002.J Mol Biol318:429-442.
Renard, M. et al., “Improving the Sensitivity and Dynamic Range of Reagentless Fluorescent Immunosensors by Knowledge-Based Design,” 2004.Biochemistry43:15453-15462.
Selvin, P.R., “Fluorescence Resonance Energy Transfer,” 1995.Methods Enzymol246:300-334.
Svensson, H.G. et al., << Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain, 2004.Biochemistry43:2445-2457.
Ueda, H. et al., << An optimized homogeneous noncompetitive immunoassay based on the antigen-driven enzymatic complementation, >> 2003.J Immunol Methods279:209-218.
Ueda, H., <<“Open Sandwich Immunoassay: a Novel Immunoassay Approach Based on the Interchain Interaction of an Antibody Variable Region.”2002.Journal of Bioscience and Bioengineering94:614-619.
Vet et al., “Multiplex detection of four pathogenic retroviruses using molecular beacons,” 1999. Multiplex detection of fourpathogenic retroviruses using molecular beacons.PNAS96(11):6394-6399.
Watrob, H.M. et al., << Two-Step FRET as a Structural Tool, >> 2003. Two-Step FRET as a Structural Tool.J. Am. Chem. Soc. 125:7336-7343.
Wehrman, T. et al., “Protein-protein interactions monitored in mammalian cells via complementation of β-lactamase enzyme fragments,” 2002.Proc Natl Acad Sci U S A99:3469-3474.
Yang, X. et al., << Homogeneous enzyme immunoassay modified for application to liminescence-based biosensors, >> 2005.Anal Biochem336:102-107.
Zhang, W.X. et al., << Time-resolved Forster resonance energy transfer assays for the binding of nucleotide and protein substrates to p38α protein kinase, 2005.Anal Biohem343:76-83.
Selvin, Paul R. 2000. “The renaissance of fluorescence resonance energy transfer.”Nature Structural Biology7(9): 730-734.
Davis , Wright, Tremaine, LLP
Mosher Mary E
Snyder Stuart W
University of Hawai'i
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