Cooling system for a slab gel electrophoresis apparatus

Details Cooling system for a slab gel electrophoresis apparatus Cooling system for a slab gel electrophoresis apparatus

1984-12-24

1986-09-16

Niebling,, John

Chemistry: electrical and wave energy

Apparatus

Coating, forming or etching by sputtering

2041828, G01N 2728

Patent

active

046121064

ABSTRACT:
Disclosed herein is a gel slab electrophoresis device having novel temperature and heat control capability. The electrophoresis device includes a sample unit having a pair of transversely-spaced first and second plates containing a gel cast, these plates having open top and bottom slots spaced therebetween. An integral part of the apparatus is a heat sink which is in thermal communication with the sample unit, the heat sink constituting a pneumatic circuit for both heat distribution and removal to and from the gel cast. There is also provided upper and lower solution chambers, both filled with conductive solutions, and both in fluid communication with the respective top and bottom portions of the gel. The apparatus also includes an arrangement for applying an electrical potential between the upper and lower solution chambers and, thereby, across the entire vertical length of the gel. Additionally provided is a refrigeration sub-system, the output of which is heat exchanged into the pneumatic circuit.

REFERENCES:
patent: 3374166 (1968-03-01), Raymond
patent: 3506554 (1970-04-01), Broome
patent: 3719580 (1973-03-01), Roberts et al.
patent: 4101401 (1978-07-01), Hoefer
Kern, D. Q., Process Heat Transfer, McGraw-Hill Book Company Inc., New York, pp. 472-474 (1950).

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