Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound
Patent
1996-08-14
1999-01-12
Saucier, Sandra E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing nitrogen-containing organic compound
435156, 435280, 435822, 435877, C12P 1302, C12P 722, C12P 4100
Patent
active
058587373
ABSTRACT:
A process is disclosed that bioconverts indene to (1S)-amino-(2R)-indanol substantially free of any of its stereoisomers, by the action of a strain of P. putida or Rhodococcus sp., followed by various chemical step(s), e.g., chiral specific crystallization, treatment with strong acid in the presence of acetonitrile.
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Buckland Barry C.
Chartrain Michel M.
Connors Neal C.
Gailliot Francis P.
Greasham Randolph L.
Merck & Co. , Inc.
Saucier Sandra E.
Walton Kenneth R.
Winokur Melvin
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