Conversion of hydroxymethyl-iminodiacetic acid to phosphonomethy

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus acids or salts thereof

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562568, C07C22900, C07F 938

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active

053129725

ABSTRACT:
A process for preparing N-phosphonomethyl iminodiacetic acid wherein solutions of an alkali metal salt of IDA are reacted with formaldehyde so as to form the alkali metal salt of hydroxymethyliminodiacetic acid (HMIDA). The HMIDA can be subsequently reacted with a phosphorous source such as phosphorous acid to produce PMIDA in good yield.

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Fields, J. Am. Chem. Soc., vol. 74, pp. 1528-1531 (1952).
Weygand, "Preparative Organic Chemistry," pp. 732-736 (1972).

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