Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-02-07
2006-02-07
Wax, Robert A. (Department: 1653)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C514S012200, C530S350000, C530S388800
Reexamination Certificate
active
06994979
ABSTRACT:
Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and Bcl-XLare identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing apoptosis are described, together with methods for identifying molecules that induce apoptosis through interaction with Bcl-2-family members.
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Guo Bin
Kolluri Siva Kumar
Lin Bingzhen
Reed John C.
Zhang Xiao-kun
Knobbe Martens Olson & Bear LLP
Modesi Robert B.
The Burnham Institute
Wax Robert A.
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