Conversion of 15-beta to 15-alpha 5,6,7-trinor-4,8-inter-m-pheny

Details Conversion of 15-beta to 15-alpha 5,6,7-trinor-4,8-inter-m-pheny Conversion of 15-beta to 15-alpha 5,6,7-trinor-4,8-inter-m-pheny

1992-11-20

1995-05-30

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30792

Patent

active

054203104

ABSTRACT:
The present invention provides a process for preparing 5,6,7-trinor-4,8-inter-m-phenylene PGI.sub.2 derivative using 3a,8b-cis-dihydro-3H-5,7-dibromocyclopenta[b]benzofuran as a starting material, as well as compounds which are intermediates.

REFERENCES:
patent: 4474802 (1984-10-01), Ohno et al.
Grynkiewicz et al., Tetrahedron, vol. 32, pp. 2109-2111 (1976).

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