Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles
Patent
1999-03-31
2000-08-22
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitriles
558355, 558401, 544 581, 544175, 544395, 546230, 548577, C07C25300, C07D27910, C07D26530, C07D21160, C07D20704
Patent
active
061075086
ABSTRACT:
The present invention relates to processes for the production of .alpha.-aryl-.beta.-ketonitriles, which serve as synthetic intermediates in the preparation of a series of biologically important molecules such as corticotropin releasing factor (CRF) receptor antagonists.
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Labadie, Sharada, 3-Aryl-2,4,-Pentanediones From 3,5-Dimethyl-4-Iodoisoxazoles: An Application of a Palladium-Catalyzed Cross-Coupling Reaction, Synthetic Communications, 24(5), 709-719, 1994.
Ma Philip
Oh Lynette May
Zhou Jiacheng
Dolan Peter L.
DuPont Pharmaceuticals Company
Raymond Richard L.
Truong Tamthom N.
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