Controlling protein levels in eucaryotic organisms

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides with at least one nonpeptide bond other than a...

Reexamination Certificate

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C435S070100, C435S007100, C435S113000, C435S114000, C435S116000

Reexamination Certificate

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10345281

ABSTRACT:
The invention relates to novel compounds comprising a ubiquitination recognition element and a protein binding element. The invention also relates to the use of said compounds for modulating the level and/or activity of a target protein. The compounds are useful for the treatment of disease such as infections, inflammatory conditions, cancer and genetic diseases. The compounds are also useful as insecticides and herbicides.

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