Controlling bone resorption with pyrroloquinoline quinone (PQQ)

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514108, 514292, A61K 31675, A61K 3144

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active

056165765

ABSTRACT:
PQQ and PQQ-generating compounds inhibit osteoclast cell formation and bone resorption, and those compounds can be used to treat medical conditions characterized by undesired bone resorption. PQQ-phosphonates that target osteoclasts at the bone-mineral interface are particularly useful in this regard.

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