Controlled release tablet formulation

Details Controlled release tablet formulation Controlled release tablet formulation

1994-03-02

1995-10-17

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424458, 424465, 424468, 424469, 424482, 424484, 424494, 424497, A61K 922, A61K 932

Patent

active

054588880

ABSTRACT:
The present invention provides a controlled release dosage form which may be made using a blend having an internal drug containing phase and an external phase which comprises a polyethylene glycol polymer which has a weight average molecular weight of from 3000 to 10000. The dosage formulation may be pressed into tablets or it may be formed directly into discrete orally administrable shapes by pressing the blend into a cavity which is sized to accept a volume of the blend which is equivalent to one dosage unit. A plurality of cavities may be formed in a strip of plastic which may be sealed after the blend of the invention is pressed in place to form a plurality of unit doses of a drug.

REFERENCES:
patent: 3108046 (1963-10-01), Harbit
patent: 4380534 (1983-04-01), Fukui et al.
patent: 4415547 (1983-11-01), Yu et al.
patent: 4432965 (1984-02-01), Keith et al.
patent: 4684516 (1987-08-01), Bhutani
patent: 4710384 (1987-12-01), Rotman
patent: 4755386 (1988-07-01), Hsiao et al.
patent: 4874614 (1989-10-01), Becker
patent: 5085033 (1992-02-01), Graham
patent: 5139790 (1992-08-01), Snipes

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