Controlled release tablet

Details Controlled release tablet Controlled release tablet

1986-08-28

1989-03-28

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

A61K 944

Patent

active

048162620

ABSTRACT:
The disclosure herein describes a controlled release tablet which includes a core formed of a solid mixture having a hydrophilic releasable agent; the core has a central hole and is coated, on all faces except that bordering the hole with a hydrophobic material. The thickness of the core gradually increases from the hole to the outer border, this being a factor in the rate of release of the mixture through the hole. One application of such a tablet is for the controlled release of a therapeutic agent in the field of drug delivery systems.

REFERENCES:
patent: 216107 (1879-06-01), Richards
patent: 2312381 (1943-03-01), Bickenheuser
patent: 3113076 (1963-12-01), Jacobs
patent: 3146169 (1964-08-01), Stephenson et al.
patent: 3279995 (1966-10-01), Reid
patent: 4218433 (1980-08-01), Kooichi et al.
patent: 4663147 (1987-05-01), De Prince

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