Controlled release powder and process for its preparation

Details Controlled release powder and process for its preparation Controlled release powder and process for its preparation

1988-03-17

1990-07-10

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 48, 424440, 424441, 424464, 424469, 424470, 424484, 424486, 424487, 424488, 424489, 424494, 424497, A61K 914, A61K 916

Patent

active

049405888

ABSTRACT:
A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.

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