Controlled release powder and process for its preparation

Details Controlled release powder and process for its preparation Controlled release powder and process for its preparation

1990-07-09

1994-10-11

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

424486, 424487, 424488, 424497, 424501, 424502, 514974, A61K 958, A61K 960

Patent

active

053545567

ABSTRACT:
A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.

REFERENCES:
patent: 3996355 (1976-12-01), Lin et al.
patent: 4223006 (1980-09-01), Taskis
patent: 4280995 (1981-07-01), Loran
patent: 4361580 (1982-11-01), Peck et al.
patent: 4368197 (1983-01-01), Shefter et al.
patent: 4590068 (1986-05-01), Berthet et al.
patent: 4952402 (1990-08-01), Sparks et al.
patent: 4994260 (1991-02-01), Kallstrand et al.

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