Controlled release pharmaceutical preparation containing a gastr

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424498, 424490, 424451, A61K 916

Patent

active

048226190

ABSTRACT:
A controlled release pharmaceutical preparation containing a micronized gastrointestinal irritant drug, such as potassium chloride, in a non-toxic protective balm. An irritant/balm admixture may be formed into microparticles. Alternatively, an irritant/balm admixture, may be used as the core for microcapsules. The microparticles or microcapsules may themselves be filled into a capsule or tabletted.

REFERENCES:
patent: 3903255 (1975-09-01), Gusman et al.
patent: 3970750 (1976-07-01), Brockemeyer et al.
patent: 4132753 (1979-01-01), Blichare et al.
patent: 4140756 (1979-02-01), Gallian
patent: 4259315 (1981-03-01), Lippmann et al.
patent: 4352791 (1982-10-01), Zaffaroni et al.
patent: 4483847 (1984-11-01), Augart
patent: 4574080 (1986-03-01), Roswall et al.
patent: 4675140 (1987-06-01), Sparks et al.
Chemical Abstracts, vol. 104, 1986, pp. 56319, Abstract 56321p, Skoutakis, Vasilios A. Arcchiodo, Sajir K. et al.

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