Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1992-03-23
1994-02-01
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424472, 424474, 424465, 424468, 424469, 424480, 424482, 424484, 424489, 424494, 424497, A61K 914, A61K 944, A61K 952
Patent
active
052830659
ABSTRACT:
A controlled release pharmaceutical composition in oral dosage unit form comprising a tablet comprising a therapeutically effective number of active spherical granules comprising an effective amount of active medicament, a pharmaceutically acceptable normally solid diluent adapted to form a diffusable matrix for the active medicament and an optional pharmaceutically acceptable excipient; and a number of compressible spherical granules comprising a mono- or di-saccharide, an optional pharmaceutically acceptable normally solid diluent adapted to form a diffusable matrix, an optional active medicament and/or an optional pharmaceutically acceptable excipient wherein the average compressive yield of the compressible spherical granules is less than the average compressive yield of the active spherical granules is provided. A method for the preparation and for the administration of the above defined composition is provided as well.
REFERENCES:
patent: 2687367 (1954-08-01), Burrin
patent: 2887436 (1959-05-01), Klioze
patent: 2953497 (1960-09-01), Press
patent: 3080294 (1963-03-01), Shepard
patent: 3115441 (1963-12-01), Hermelin
patent: 3344029 (1967-09-01), Berger
patent: 3865935 (1975-02-01), Amann
patent: 4012498 (1977-03-01), Kornblum
patent: 4173626 (1979-11-01), Dempski et al.
patent: 4177254 (1979-12-01), Khan
patent: 4353887 (1982-10-01), Hess et al.
patent: 4444769 (1984-04-01), Blume
patent: 4483847 (1984-11-01), Augart
patent: 4572833 (1986-02-01), Pedersen
patent: 4606909 (1986-08-01), Bechgaard et al.
patent: 4784858 (1988-11-01), Ventouras
patent: 4808413 (1989-02-01), Joshi
patent: 4837030 (1989-06-01), Valorose, Jr. et al.
patent: 4844910 (1989-07-01), Leslie et al.
patent: 4853229 (1989-08-01), Theeuwes
patent: 4880830 (1989-11-01), Rhodes
Doyon Daniel J.
Ganesan Madurai G.
Preston Wendy A.
Sheth Nitin V.
American Cyanamid Company
Costigan James V.
Jackson H. G.
Page Thurman K.
Spear James M.
LandOfFree
Controlled release pharmaceutical compositions from spherical gr does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Controlled release pharmaceutical compositions from spherical gr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Controlled release pharmaceutical compositions from spherical gr will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-578307