Controlled release pharmaceutical compositions for the oral admi

Details Controlled release pharmaceutical compositions for the oral admi Controlled release pharmaceutical compositions for the oral admi

1997-09-09

1999-02-16

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424464, 424486, 424487, 5147725, 427 215, A61K 948

Patent

active

058717757

ABSTRACT:
Controlled release pharmaceutical compositions for the oral administration of nifedipine are disclosed which comprise an amorphous coprecipitate of nifedipine and polyvinylpyrrolidone with suitable excipients. The release rate may be varied from 8 to 24 hours by varying the amounts of the cellulose derivative, the carboxypolymethylene and the lactose.

REFERENCES:
patent: 4606911 (1986-08-01), Hayashi et al.
patent: 5145683 (1992-09-01), Rhodes
patent: 5209933 (1993-05-01), MacFarlane et al.
European Search Report, Mar. 24, 1997, Examiner Ventrua Amat, A.

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