Controlled release of pharmaceutically active substances from co

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424490, 424493, 4284022, 264 41, 264 43, 264 46, A61K 950

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active

057595828

ABSTRACT:
A controlled-release pharmaceutical composition comprising a pharmaceutically active water soluble protein, peptide, glycoprotein, or mixture thereof, encapsulated in the form of microspheres by a coating of a crosslinked coacervate of gelatin and chondroitin sulfate, as well as processes for the preparation thereof.

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Azhari, et al., Protein Release from Enzymatically-Degradable Chondroitin-Sulfate/Gelatin Microspheres, Proceed. Intern. Symp. Control. Rel. Bioact. Master., 18:617-618, 1991, Controlled Release Society, Inc.

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