Controlled release of pharmaceutically active substances for imm

Details Controlled release of pharmaceutically active substances for imm Controlled release of pharmaceutically active substances for imm

1996-01-16

1999-01-19

Minnifield, Nita

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

4242771, 4242781, 424450, 424852, 424 9321, 514 2, 514 8, 514 44, A61K 4800, A61K 3900, A61K 4500, A61K 4304

Patent

active

058611592

ABSTRACT:
A method of stimulating a systemic immune response to a tumor cell or antigen associated with a pathogen by administering a mixture of a controlled release vehicle containing an immunopotentiating agent and antigen is described. The method of the invention provides sustained release of therapeutic compounds to allow a host immune system to ameliorate local as well as metastatic tumors in the host. The immunopotentiating agent is typically a cytokine such as tumor necrosis factor, GM-CSF, interleukin or interferon, for example.

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