Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation
Patent
1997-03-12
1998-06-16
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Ophthalmic preparation
5147723, A61K 3174
Patent
active
057665800
ABSTRACT:
The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.
REFERENCES:
patent: 4141973 (1979-02-01), Balazs
patent: 4303637 (1981-12-01), Shell et al.
patent: 4305927 (1981-12-01), Theeuwes et al.
patent: 4668506 (1987-05-01), Bawa
patent: 4713244 (1987-12-01), Bawa et al.
patent: 4863457 (1989-09-01), Lee
patent: 4911920 (1990-03-01), Jani et al.
patent: 4931279 (1990-06-01), Bawa et al.
patent: 5007913 (1991-04-01), Dulebohn et al.
patent: 5093126 (1992-03-01), Jani et al.
patent: 5098443 (1992-03-01), Parel et al.
patent: 5318780 (1994-06-01), Viegas et al.
Schoenwald, 1993, "Pharmacokinetics in Ocular Drug Delivery" (chapter 10), Biopharmaceuticals of Ocular Drug Delivery, CRC Press, Inc., Boca Raton, FL.
Hayakawa et al. 1983, Macromolecules 16:1642.
Galin Miles A.
Israel Stanley C.
Salamone Joseph C.
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