Controlled release of miotic and mydriatic drugs in the anterior

Details Controlled release of miotic and mydriatic drugs in the anterior Controlled release of miotic and mydriatic drugs in the anterior

1997-03-12

1999-10-12

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424427, 424489, A61F 200, A61K 914

Patent

active

059651520

ABSTRACT:
The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and line the anterior segment from potential damage and simultaneously providing sustained delivery of a miotic or mydriatic agent. The present invention provides for compositions which comprise a viscoelastic polymer, wherein sustained release of a miotic or mydriatic agent is mediated by ionic interactions, as well as for compositions wherein sustained release of a miotic or mydriatic agent is mediated by microcapsules or copolymer micelles.

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