Controlled release of anticancer agents from biodegradable polym

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424 22, 424 78, A61K 926, A61K 3174, A61K 4700

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active

044193408

ABSTRACT:
Polymeric articles for controllably dispensing anticancer agents are disclosed which are formed from biodegradable polymeric materials containing the agents.

REFERENCES:
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patent: 3887699 (1975-06-01), Yolles
patent: 3904663 (1975-09-01), Tobe et al.
patent: 3976071 (1976-08-01), Sadek
patent: 3991766 (1976-11-01), Schmitt et al.
Merck Index 9th Ed. (1976) Merck & Co. Rahway, N.J., p. 359 Entry 2751 Cyclophosphamide, Antineoplastic; Antineoplastic p. 456 Entry 3428 Doxorubicin (U.S. 3590 028 (1971) Farmitalia).
Yolles et al., J. Pharm. Sci. 64(1): 115-116 Jan. 1975 "Timed Release Depot for Anticancer Agents".
Yolles et al., Acta Pharmaceuitca Suecica 15(5): 382-388 (1978), "Timed-Release Depot for Anticancer Agents II."
Yolles et al., Parenteral Drug Assn. Jl. 32(4): 188-191 (1978), Timed Release Depot for Anticancer Drugs: "Release of Drugs Covalently Bonded to Polymers".

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