Controlled-release nifedipine

Details Controlled-release nifedipine Controlled-release nifedipine

1996-10-28

1999-02-16

Harrison, Robert H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424497, 514356, 514964, A61K 916, A61K 958

Patent

active

058717765

ABSTRACT:
A nifedipine formulation for oral administration is described that provides controlled, constant release of the pharmaceutical for about twenty four hours after a short delay following oral administration. There is also provided a method for preparing a controlled release formulation of nifedipine, which method includes coating pellets with multiple nifedipine-containing layers, along with an outer controlled release coating comprised of a water permeable polymer and lubricant/glidant. The pellets are then cured at an elevated temperature over several days. A method of using the formulations of the present invention for the treatment of patients is also described.

REFERENCES:
patent: 4765990 (1988-08-01), Sugimoto et al.
patent: 4814175 (1989-03-01), Tack et al.
patent: 4874613 (1989-10-01), Hsaio
patent: 4900557 (1990-02-01), Dell et al.
patent: 5145683 (1992-09-01), Rhodes
patent: 5204121 (1993-04-01), Buecheler et al.
patent: 5258186 (1993-11-01), Ohmura
patent: 5286493 (1994-02-01), Oshlack et al.
patent: 5292461 (1994-03-01), Juch et al.
patent: 5496561 (1996-03-01), Okada et al.
patent: 5543154 (1996-08-01), Rork et al.
patent: 5567441 (1996-10-01), Chen
patent: 5594013 (1997-01-01), Trigger

Affiliated with

Also associated with

Rating

Controlled-release nifedipine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Controlled-release nifedipine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Controlled-release nifedipine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2059892