Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1985-12-20
1989-02-07
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424465, 424462, 424470, 424476, 424480, 424488, 514570, 514781, A61K 922, A61K 926
Patent
active
048030791
ABSTRACT:
A controlled release tablet for once-daily oral administration of about 500-1200 mg of naproxen or naproxen sodium, said tablet comprising a homogeneous matrix comprising about 4-9 weight percent of hydroxypropyl methylcellulose having a number average molecular weight in the range of from about 80,000 to about 130,000, about 81-96 weight percent naproxen or naproxen sodium, and 0.1 to about 2 weight percent of a pharmaceutically acceptable lubricating agent, and optionally including a pharmaceutically acceptable coating.
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Hsiao Charles H.
Kent John S.
Krubiner Alan M.
Moran Tom M.
Rose Shep K.
Syntex (U.S.A.) Inc.
Wise Ellen J.
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