Controlled release nanoparticle having bound oligonucleotide...

Details Controlled release nanoparticle having bound oligonucleotide... Controlled release nanoparticle having bound oligonucleotide...

2003-06-06

2010-06-01

Naff, David M (Department: 1657)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S486000, C424S489000, C435S006120, C435S180000, C435S182000, C436S531000, C436S535000, C514S002600, C530S817000

Reexamination Certificate

active

07727969

ABSTRACT:
The present invention relates to a conjugate that includes a nucleic acid ligand bound to a controlled release polymer system, a pharmaceutical composition that contains the conjugate, and methods of treatment using the conjugate. The controlled release polymer system includes an agent such as a therapeutic, diagnostic, prognostic, or prophylactic agent. The nucleic acid ligand that is bound to the controlled release polymer system, binds selectively to a target, such as a cell surface antigen, and thereby delivers the controlled release polymer system to the target.

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