Controlled-release multiple units pharmaceutical formulation

Details Controlled-release multiple units pharmaceutical formulation Controlled-release multiple units pharmaceutical formulation

1986-02-27

1988-09-20

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424469, 424470, 424482, 424488, A61K 922, A61K 926, A61K 952

Patent

active

047724757

ABSTRACT:
A pharmaceutical controlled-release individual unit or multiple units formulation in which the individual unit comprises a granulation product obtained by adding a release controlling agent to a mixture of a physiologically active substance and units-forming substance(s) and granulating and resultant mixture, said granulation product (granules) being substantially not disintegrated but gradually releasing the physiologically active substance in the gastrointestinal tract.

REFERENCES:
patent: 4241086 (1980-12-01), Iwao et al.
patent: 4261970 (1981-04-01), Ogawa et al.
patent: 4305958 (1981-12-01), Fujita et al.
patent: 4438115 (1984-03-01), Nagano et al.
patent: 4469704 (1984-09-01), Sato et al.
patent: 4472398 (1984-09-01), Meszaros et al.
patent: 4495189 (1985-01-01), Meszaros et al.
patent: 4501752 (1985-02-01), Yokol et al.
patent: 4552765 (1985-11-01), Mita et al.

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