Controlled-release mucoadhesive pharmaceutical composition for t

Details Controlled-release mucoadhesive pharmaceutical composition for t Controlled-release mucoadhesive pharmaceutical composition for t

1994-05-09

1996-11-05

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424498, A61K 926

Patent

active

055715338

ABSTRACT:
Disclosed are controlled-release mucoadhesive pharmaceutical compositions for the oral administration of furosemide. This composition comprises a multiplicity of microgranules of lipophilic material which are coated with a mucoadhesive coating. This invention reduced or eliminates the diuresis peak and reduces inter-subject response variability which normally accompany conventional treatment with this drug.

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