Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1998-10-28
2000-11-07
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
A61F 200
Patent
active
061433144
ABSTRACT:
The invention provides a controlled release polymeric composition which includes a base polymer or copolymer, an organic solvent, a polymeric controlled release additive, and a biologically active agent. The polymeric controlled release additive reduces the initial burst of biologically active agent released from the polymeric composition as it is solidifying to form the solid implant. The controlled release additive is preferably a poly(lactide-co-glycolide)/polyethylene glycol block copolymer.
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Chandrashekar Bhagya L.
Dunn Richard L.
Jarr Eileen M.
Zhou Mingxing
Atrix Laboratories, Inc.
Berman Alysia
Page Thurman K.
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