Controlled-release immunogenic formulations to modulate...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector

Reexamination Certificate

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C424S009100, C424S009200, C424S200100, C424S204100, C424S234100, C424S278100, C424S280100, C424S093100

Reexamination Certificate

active

07858093

ABSTRACT:
Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.

REFERENCES:
patent: 4990336 (1991-02-01), Silvestri et al.
patent: 2010/0021546 (2010-01-01), Kipper et al.
Gallo, R.C., “The end or the beginning of the drive to an HIV-preventive vaccine: a view from over 20 years”, Lancet, vol. 366, pp. 1894-1898, 2005.
Wang, J., et al, “Tuberculosis vaccines: the past, present and future”, Expert Rev. Vaccines, vol. 1, No. 3, pp. 341-354, 2002.
Shen, E., et al. Mechanistic relationships between polymer microstructures and drug release kinetics in bioerodible polyanhydrides. Journal of Controlled Release, vol. 82, pp. 115-125, 2002.
Kipper, M.J., et al. Design of an injectable system based on bioerodible polyanhydride microspheres for sustained drug delivery. Biomaterials, vol. 23, pp. 4405-4412, 2002.
Kipper, M. J., et al., “Polymeric Biomaterials with Tailored Microstructures, Nanostructures, and Bioactive Surface Chemistries for Drug Delivery and Tissue Engineering”,Conference Proceedings, Annual Meeting of the American Institute of Chemical Engineers, obtained from http://aiche.confex.com/aiche/2005/techprogram/P9686.HTM,(Oct. 2005),4 p.
Kipper, M. J., et al., “Single Dose Tetanus Vaccine Based on Polyanhydride Microspheres”,Conference Proceedings, Annual Meeting of the American Institute of Chemical Engineers, Abstract No. 68a, obtained from http://www.aiche.org/conferences/techprogram/paperdetail.asp?PaperID=2163&DSN=annual04,(Oct. 2005),2 p.
Determan, A. S., et al., “Encapsulation, Stabilization, and Release of BSA-FITC From Polyanhydride Microspheres”,Journal of Controlled Release, 100, (2004),97-109.

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