Controlled release formulations coated with aqueous dispersions

Details Controlled release formulations coated with aqueous dispersions Controlled release formulations coated with aqueous dispersions

1993-07-27

1996-12-03

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424482, 424417, A61K 932

Patent

active

055805787

ABSTRACT:
A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the group consisting of a systemically active therapeutic agent, a locally active therapeutic agent, a disinfecting and sanitizing agent, a cleansing agent, a fragrance agent and a fertilizing agent, overcoated with an aqueous dispersion of the plasticized water-insoluble acrylic polymer. The formulation provides a stable dissolution of the active agent which is unchanged after exposure to accelerated storage conditions.

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