Controlled release formulation of diltiazem hydrochloride

Details Controlled release formulation of diltiazem hydrochloride Controlled release formulation of diltiazem hydrochloride

1995-05-11

1996-11-26

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424451, 424452, 424456, 424464, 424465, 514781, A61K 948

Patent

active

055783210

ABSTRACT:
A pharmaceutical tablet containing diltiazem hydrochloride suitable for once daily oral administration comprising by weight not less than 30 percent diltiazem hydrochloride and from 30 percent to 70 percent hydroxypropyl methylcellulose having a number average molecular weight of at least 50,000. A two piece hard gelatin capsule containing a plurality of such tablets.

REFERENCES:
patent: 4839177 (1989-06-01), Colombo et al.
patent: 4894240 (1990-01-01), Geoghegan et al.
patent: 5000962 (1991-03-01), Sangekar et al.

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