Controlled release formulation for pharmaceutical compounds

Details Controlled release formulation for pharmaceutical compounds Controlled release formulation for pharmaceutical compounds

1992-12-22

1994-06-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424462, 424471, 424482, 424497, A61K 924, A61K 958

Patent

active

053208536

ABSTRACT:
Controlled release pharmaceutical beads are provided having a multi-layered core and a multi-layered periphery. The core contains at least (A) an inner portion having a suitable organic acid and (B) a sustainably-acid-releasing coating thereover. The periphery contains at least (A) an inner portion having a mixture of at least (i) a pharmaceutical compound and (ii) a surface-active agent, and (B) a sustainably-drug-releasing exterior coating.

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