Controlled release drug suspension delivery device

Details Controlled release drug suspension delivery device Controlled release drug suspension delivery device

1994-12-22

1996-12-10

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424471, 424473, 424479, 424480, 424482, 424470, A61K 924, A61K 932, A61K 936

Patent

active

055828388

ABSTRACT:
A device is disclosed for the controlled delivery of a beneficial agent, the device consisting of (i) a core comprising at least two layers, wherein at least one layer comprises a beneficial agent and a polymer which forms microscopic gel beads upon hydration and at least one layer which comprises a polymer which forms microscopic gel beads upon hydration; and (ii) an impermeable, insoluble coating which adheres to and surrounds the core and contains apertures which provide an area for the hydration and release of the microscopic gel beads.

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Proceed. Intern. Symp. Control Rel. Bioact. Mater., 20 (1993).
J. Pharm. Sci., 72, pp. 772-775 (1983), by Kallstrand, et al.

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