Controlled-release, drug-delivery composition

Details Controlled-release, drug-delivery composition Controlled-release, drug-delivery composition

1998-07-23

2000-04-11

Zitomer, Fred

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424 7803, 424 7012, 424 7818, 424 7824, 42840222, 526194, 526263, 526264, A61K 9113, A61K 3174, A61K 3179, A61K 31695

Patent

active

060485221

ABSTRACT:
A controlled-release, drug-delivery, emulsion composition for topical application comprising (a) the reaction product of the non-aqueous, heterogeneous polymerization of a reaction mixture of about 5-70%, preferably 10-30%, by weight, of a vinyl monomer in an oil as solvent, and a free radical initiator, optionally in the presence of a crosslinking agent and/or a surfactant, wherein the oil solvent is present in an amount sufficient to keep the resultant polymer in a stirrable state throughout the polymerization, (b) water, (c) a surfactant and (d) a pharmaceutical medicament.

REFERENCES:
patent: 5130121 (1992-07-01), Kopolow
patent: 5156914 (1992-10-01), Shih
patent: 5189102 (1993-02-01), Tsubuko

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