Controlled release delivery system by an osmotic bursting mechan

Details Controlled release delivery system by an osmotic bursting mechan Controlled release delivery system by an osmotic bursting mechan

1975-01-09

1976-04-27

Medbery, Aldrich F.

Surgery

Respiratory method or device

Ozone or ion generation

222 54, 222491, 128272, A61M 700, B65D 3508

Patent

active

039527417

ABSTRACT:
An osmotic dispenser comprised of (1) a water permeable membrane forming part or all of the walls of an enclosure surrounding (2) an active agent, and in some cases (3) an additional compound known as an osmotic attractant which together exhibits an osmotic pressure against water. When placed in an aqueous environment water is osmotically drawn into the enclosure by the combined action of the agents (2) and (3) which distends and swells the enclosure until the membrane or some other part of the enclosure wall reaches the point of ultimate elongation and a portion of the wall yields and ruptures releasing the contents of the enclosure to the environment.

REFERENCES:
patent: 3247066 (1966-04-01), Milosovich
patent: 3710795 (1973-01-01), Higuchi
patent: 3760984 (1973-09-01), Theewes
patent: 3765414 (1973-10-01), Arlen
patent: 3797492 (1974-03-01), Place
patent: 3832458 (1974-08-01), Merrill
patent: 3840009 (1974-10-01), Michaels

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