Controlled release compositions

Details Controlled release compositions Controlled release compositions

1992-01-17

1994-10-04

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424486, A61K 902

Patent

active

053524551

ABSTRACT:
Controlled release compositions comprising a water swellable carrier and an active material having crenellated surface exhibit improved release properties. Suppositories and pessaries of generally cylindrical shape having four or five crenellations spaced equally around the perimeter and extending substantially along the length of the cylinder are preferred. Suppositories comprising four or five rounded crenellations which release morphine sulphate are especially useful.

REFERENCES:
patent: 4767627 (1988-08-01), Caldwell
patent: 4837111 (1989-06-01), Deters
patent: 5079009 (1992-01-01), Embrey

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