Controlled release composite core coated microparticles

Details Controlled release composite core coated microparticles Controlled release composite core coated microparticles

1985-12-02

1986-11-18

Kittle, John E.

Stock material or miscellaneous articles

Coated or structually defined flake, particle, cell, strand,...

Particulate matter

424 31, 424 35, 427 3, 427213, A61K 930, A61K 950, A61K 958, B05D 702

Patent

active

046235884

ABSTRACT:
A process for preparing coated microparticles, which process comprises preparing a solvent solution of an active ingredient to be encapsulated and a film-forming polymer, removing the solvent to provide a dry, composite, uniform admixture of the active ingredient and the polymer material, reducing the composite admixture to a defined smaller particle size distribution, coating the reduced composite core particles in a fluidized bed, with a uniform defined wall thickness of the same or substantially the same film-forming polymer material to provide composite core coated microparticles.

REFERENCES:
patent: 3089824 (1963-05-01), Wurster
patent: 4568559 (1986-02-01), Nuwayser et al.

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