Controlled release combination of carbidopa/levodopa

Details Controlled release combination of carbidopa/levodopa Controlled release combination of carbidopa/levodopa

1988-07-25

1989-05-23

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424468, 424486, 424488, A61K 920, A61K 922, A61K 926

Patent

active

048329576

ABSTRACT:
A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists of the two drugs uniformly dispersed in a polymer vehicle at a concentration that is greater than the solubility of either drug in the polymer. Treatment of parkinsonism with the controlled release formulation provides several advantages over treatment with the standard carbidopa/levodopa combinations presently employed.

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Chem Abs. 78 (No. 16) (p. 13) Tanemura et al.

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