Controlled release combination of carbidopa/levodopa

Details Controlled release combination of carbidopa/levodopa Controlled release combination of carbidopa/levodopa

1989-12-01

1991-01-08

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424470, 424486, 424487, 424 81, A61K 922, A61K 926, A61K 3178

Patent

active

049834002

ABSTRACT:
A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists of the two drugs uniformly dispersed in a polymer vehicle at a concentration that is greater than the solubility of either drug in the polymer. Treatment of parkinsonism with the controlled release formulation provides several advantages over treatment with the standard carbidopa/levodopa combination presently employed.

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