Controlled release chromium picolinate

Details Controlled release chromium picolinate Controlled release chromium picolinate

1998-01-21

2000-12-05

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424451, 424454, 424456, 424461, 424462, 424463, 424476, 424479, 424480, 424482, 424490, A61K 922

Patent

active

061563471

ABSTRACT:
The present invention relates to controlled/extended release oral dosage forms of chromium picolinate. Chromium picolinate is a common and effective biologically active form of chromium. As such, it has beneficial nutritional and therapeutic effects including improved insulin metabolism and lipid lowering activity.
The controlled dosage form of the present invention can be provided in various ways, including matrix formulations such as matrix tablets or multiparticulate formulations like micro capsules or coated pellets put into hard gelatin capsules. This provides effective drug delivery for extended periods of time, at relatively stable, optimal plasma peak values, with minimal undesirable side effects.
The invention provides effective controlled/extended release oral dosage formulations of chromium picolinate and processes for their preparation.

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patent: 5798101 (1998-08-01), Haveson
patent: 5849338 (1998-12-01), Richardson et al.
patent: 5891465 (1999-04-01), Keller et al.

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